- Mres Studentship In Microbiology

Tech
2015-12-08 03:53:43

MRes Studentship in Microbiology

Deadline

2015-12-16

Value of Scholarship

Level of Study

Country Tenable

Renewable

MSc (Masters by Research), 12 Months duration, Full-Time.

Funding

This is a fees-only studentship (UK rate fees only / all laboratory & reagent costs are paid by the School of Life, Sport and Social Sciences) over 12 months.

Project Reference PG4CT

Area of Research

Infection, Pathogenicity, Biotechnology

Project Description

This project is based in the Microbiology section of the School of Life, Sport & Social Sciences. The project is led by Dr Clare Taylor whose research is primarily focused on understanding host-microbe interactions, particularly of intracellular bacteria that cause human infection.

The current project is exploring cobalt-mediated gene expression inÂ Salmonella entericaÂ sv. Typhimurium with a view to understanding how cobalt contributes to bacterial pathogenicity, and to exploit these findings to develop novel medical therapies.

Cobalt is required for incorporation into cobalamin (vitamin B₁₂) which is synthesisedÂ de novoÂ under anaerobic conditions and is required for metabolism of 1,2-propanediol and ethanolamine which act as sources of carbon and nitrogen whenÂ SalmonellaÂ is in the gut. Therefore sensing Co²⁺Â from the environment, and maintaining Co²⁺Â homeostasis, to avoid metal-mediated toxicity, is required for vitamin B₁₂Â biosynthesis and successful establishment ofÂ SalmonellaÂ leading to infection.

This laboratory-based project will focus on characterising genes that interact with cobalt and explore how we might exploit the findings.

Applicants must have an undergraduate degree in a relevant discipline.

Contact Dr Clare Taylor (cl.taylor@napier.ac.uk) for further information.

Start Date: The studentship starts on 1st February 2016.

Application Deadline: All applications must be received by Wednesday 16th December 2015.

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