PhD Studentship Validation of Novel PET Imaging Biomarkers
Deadline
Value of Scholarship
Level of Study
Country Tenable
Renewable
No
PhD Studentship Validation of Novel PET Imaging Biomarkers

To celebrate the University's research successes, the University of Hull is offering a PhD scholarship for candidates applying for the following project.

Closing Date: 14th August 2013

Start Date: 30 September 2013.  

Informal enquiries:

Dr.C. Cawthorne                +44 (0)1482 466776        c.cawthorne@hull.ac.uk

Prof.J. Greenman              +44 (0)1482 465409 j.greenman@hull.ac.uk

How to apply

Visit our website via the ‘Apply’ button below.

Project outline

An exciting opportunity is available starting 30 September 2013, for a fully funded full time PhD studentship to develop novel imaging biomarkers for cancer.

Estrogen receptor-a is expressed in most breast cancers, and patients with ERa-positive (ERa+) tumours have longer overall survival and better response to hormone based therapies. The Progesterone Receptor (PR) is an estrogen-regulated gene, and there is evidence that PR expression in response to ER stimulation is predictive of response to anti-estrogenic therapies. Although ER and PR status are measured immunohistochemically in current clinical practice, molecular imaging of this pathway offers the ability to assess the whole disease burden in a patient longitudinally, allowing the assessment of heterogeneity and changes in response to therapy that may inform clinical management. The aim of this project is to screen a library of putative PR binding PET imaging agents for use as imaging biomarkers, using a wide range of in vitro and in vivo techniques. The project will make use of the recently installed Bioscan PET/CT scanner at the University of Hull, part of the new PET Research Centre.

Applicants should be highly motivated and have:

  • A minimum Upper Second Class honours degree in a relevant subject from a recognised Institution
  • Previous experience in the biological analysis of tissue will be an advantage

Further details

This full-time UK/EU PhD scholarship will include fees at the 'home/EU' student rate and maintenance of £13,726 (in 2013/14) for three years, depending on satisfactory progress.

PhD students at the University of Hull are required to follow modules for research and transferable skills development and gain a Masters level Certificate or Diploma in Research Training in addition to their research degree.

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